Xarelo is a new Novel Oral Anticoagulant category (NOAC) blood-thinner medication manufactured by Johnson & Johnson and Bayer AG. It is used for treating several different conditions, including deep vein thrombosis, pulmonary embolism and atrial fibrillation. However, Xarelto is considered to be a high-risk medication and ruled responsible for serious injuries like liver damage symptoms and the deaths of several patients. Hundreds of lawsuits have been filed against the manufacturers of the drug as a result of so many individuals suffering uncontrollable internal bleeding to the point that even after being hospitalized doctors still had no way of stopping it. Unlike other similar drugs like Warfarin, there is no known antidote for reversing the effects of Xarelto, so once life-threatening bleeding takes place; the patient is at risk of death or severe injuries.
However, there are also several other potentially very serious or fatal side effects for Xarelto that are still under post-marketing investigation currently since the drug was introduced in 2008 to the worldwide market. Risk of liver damage is one of the more alarming adverse reactions that is associated with the drug Xarelto. Liver damage symptoms caused by Xarelto have been investigated for being a potential risk for individuals taking Xarelto medication. There have also been several Xarelto-induced liver injury cases that have been reported. These include several cases of acute liver failure. The results from three big international pharmacovigilance databases were recently analyzed. The analysis revealed that Xarelto was suspected to be a cause in a large number of hepatic adverse cases.
In addition to gastrointestinal bleeding and internal hemorrhage, liver damage symptoms are the most reported Xarelto side effect. It can be discovered in blood tests by elevated enzymes AST and ALT. The 4 Record study results showed that of the 6,183 patients that were treated with rivaroxaban, 2.33% had increased liver enzyme (transaminase) levels that were over 3 times higher than ULN (upper limit of normal). There were two other cases where patient showed liver damage symptoms after being treated with Xarelto which were published recently in the Journal of American Medical Association, which further confirms this drug’s alarming potential hepatotoxicity.
Another thing that should be noted is that more than two-thirds of the drug, which is administered orally, is eliminated via urine or bile following hepatic metabolism. If liver function has been comprised, the blood levels of the drug may potentially increase due to the liver being unable to eliminate a sufficient quantity of Xarelto out of the body. However, this medication’s main selling points were the fact that blood monitoring was not required and its purported safety. These points were advertised widely over the internet and television.
Without any blood monitoring, it results in patient not being aware if the effects from the drug have increased to the level of growing potentially dangerous due to an increased risk for bleeding accidents. Therefore, this requires that an appropriate adjustment to the dosage be made.
Since being treated with Xarelto can potentially be associated with symptomatic and severe liver damage symptoms and consequently bleeding risk, the physician and patient both need to be fully informed about this potentially significant danger. The drug label should include a warning about the potential symptomatic liver damage; otherwise patients who suffer liver injury as a Xarelto side effect have the right to file a lawsuit in reference to misleading information being provided by the manufacturers.
There are a number of side effects associated, and one of the most dangerous is internal bleeding signs, which can lead to death. People have filed lawsuits against Bayer as a result of internal bleeding. They filed lawsuits claiming Bayer did not warn of internal bleeding.
Bayer Healthcare, as well as Johnson & Johnson’s Janssen subsidiary has been hit with a number of product liability lawsuits. The lawsuits have been filed on behalf of people from all around the country. These people have suffered from internal bleeding signs and severe bleeding injuries as a result of Xarelto.
The date for the trials have been set, and the truth is that litigation against Xarelto just keeps on growing because new lawsuits are filed daily, and one of the most recent ones come from a woman in Florida. She claims the medicine caused her husband to die because it leads to fatal internal bleeding signs. The litigation is still in the stages of pretrial, and the dates have already been pushed a number of times, but this time around there are dates for the first two trials, with one being on February 6, 2017 and the other being on March 13, 2017.
The third trial is going to be held in Mississippi on April 24, 2017, and it will also be held on May 30, 2017 in the state of Texas and only these four cases will be heard during the bellwether trials and this is because of the number of lawsuits that have been filed. You may be wondering why these four cases have been chosen and there is a reason for this. The lawsuits were chosen because they are considered to be the most representative cases.
In Xarelto MDL, the defendants will be the manufacturers of Xarelto, which is Janssen Pharmaceuticals, and Bayer AG, and the plaintiffs are accusing the companies of negligence because they are accused of not properly warning people about the dangers of the medicine. The medicine’s side effects don’t include internal bleeding signs episodes that may lead to a person dying and there is nothing on the market that can reverse the medicine’s side effects, and the plaintiffs are accusing the companies of knowing this, yet they still chose to market the medicine and advertise it as a safer drug to use then their competitors’ drugs.
In December 2014 was when MDL was consolidated and since then, there have been a number of lawsuits filed and some of the damages include pain and suffering, as well as loss of wages, medical treatment and even funeral costs. If you have ever taken the medicine or someone you know has, and you or they have experienced internal bleeding signs, then you should speak with an advocate as soon as possible, as they will be able to answer some questions for you. Keep in mind the amount of money you can recover via a lawsuit does depend on a number of factors, such as age, the extent of the injury and whether or not the person died and whether or not the patient had any dependents.